1. Outcomes to PhDs Conferred < MD-PhD Program
Adriana Cherskov,“Cellular and molecular features of cerebellar evolution in primates” Mentor: Nenad Sestan, MD, PhD; Interdepartmental Neuroscience Program.
Adriana Cherskov,“Cellular and molecular features of cerebellar evolution in primates” Mentor: Nenad Sestan, MD, PhD; Interdepartmental Neuroscience Program
2. Cerebellar associative sensory learning defects in five mouse ...
9 jul 2015 · Adriana Cherskov. Department of Molecular Biology and Princeton Neuroscience Institute, Princeton University, Princeton, United States ...
Sensory integration difficulties have been reported in autism, but their underlying brain-circuit mechanisms are underexplored. Using five autism-related mouse models, Shank3+/ΔC, Mecp2R308/Y, Cntnap2-/-, L7-Tsc1 (L7/Pcp2Cre::Tsc1flox/+) and patDp(15q11-13)/+, we report specific perturbations in delay eyeblink conditioning, a form of associative sensory learning requiring cerebellar plasticity. By distinguishing perturbations in the probability and characteristics of learned responses, we found that probability was reduced in Cntnap2-/-, patDp(15q11-13)/+, and L7/Pcp2Cre::Tsc1flox/+, all associated with Purkinje-cell/deep-nuclear gene expression, along with Shank3+/ΔC. Amplitudes were smaller in L7/Pcp2Cre::Tsc1flox/+ as well as Shank3+/ΔC and Mecp2R308/Y, which are associated with granule-cell pathway expression. Shank3+/ΔC and Mecp2R308/Y also showed aberrant response timing and reduced Purkinje-cell dendritic spine density. Overall, our observations are potentially accounted for by defects in instructed learning in the olivocerebellar loop and response representation in the granule cell pathway. Our findings indicate that defects in associative temporal binding of sensory events are widespread in autism mouse models.
3. [PDF] FOSTERING LEADERSHIP - Sustainability at Princeton
• Pilot a single-stream recycling program and compare it with the existing ... and Adriana Cherskov '14. (Photo by Chris Lillja). Pictured from left are ...
4. [PDF] 20 May 2024 - Yale University
20 mei 2024 · Adriana Cherskov. BA, Princeton University; MPhil, University of ... The Role of Microglia in the Developing Rostral Migratory Stream.
5. Advanced search - IRAD Research Portfolio
CHERSKOV, ADRIANA, CHERTOFF, MARK E, CHESLOW, LARA, CHESS, ANDREW J, CHESS ... STREAM BIOMEDICAL INC, STREAM BIOMEDICAL, INC. STRESS THERAPEUTICS INC ...
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6. au:"Walsh, Christopher" (696) - BVS
... stream defects primarily result from disordered cell-cell communication ... Cherskov, Adriana; Emery, Sarah B; Fasching, Liana; Jones, Attila; Moldovan ...
7. Masahiko WATANABE (Faculty of Medicine Physiological Science ...
... stream is well known, but the endocrine hormonal control mechanisms of ... Adriana Cherskov, Taisuke Miyazaki, Masahiko Watanabe, Toru Takumi, Masanobu ...
Enhancement of Haloperidol-Induced Catalepsy by GPR143, an L-Dopa Receptor, in Striatal Cholinergic Interneurons.
8. Lhx6 Activity Is Required for the Normal Migration and Specification ...
21 mrt 2007 · ... Stream · Abstract · Fulltext · PDF · Neuronal Death Resulting from Targeted ... Miller, Adriana Cherskov, Mo Yang, Anahita Amiri, Gianfilippo ...
The cerebral cortex contains two main neuronal cell populations, the excitatory glutamatergic (pyramidal) neurons and the inhibitory interneurons, which synthesize GABA and constitute 20–30% of all cortical neurons. In contrast to the mostly hom*ogeneous population of projection neurons, cortical interneurons are characterized by remarkable morphological, molecular, and functional diversity. Among the markers that have been used to classify cortical interneurons are the calcium-binding proteins parvalbumin and calretinin and the neuropeptide somatostatin, which in rodents identify mostly nonoverlapping interneuron subpopulations. Pyramidal neurons are born during embryogenesis in the ventricular zone of the dorsal telencephalon, whereas cortical interneurons are generated in the subpallium and reach the cortex by tangential migration. On completion of tangential migration, cortical interneurons switch to a radial mode of migration and enter the cortical plate. Although the mechanisms that control the generation of interneuron diversity are currently unknown, it has been proposed that their site of origin in the ventral forebrain determines their specification into defined neurochemical subgroups. Here, we show that Lhx6 , a gene induced in the medial ganglionic eminence and maintained in parvalbumin- and somatostatin-positive interneurons, is required for the specification of these neuronal subtypes in the neocortex and the hippocampus. We also show that Lhx6 activity is requi...
9. Takumi Toru (00222092) - KAKEN — Researchers
... stream to study autonomic nervous and neuroendocrine system. Place of ... Adriana Cherskov, Taisuke Miyazaki, Masahiko Watanabe, Toru Takumi, Masanobu ...
Affiliation (Current)：神戸大学,医学研究科,教授, Research Field：Biological Sciences,Biological Sciences,Basic / Social brain science,Pathological medical chemistry,Pathological medical chemistry, Keywords：神経科学,遺伝子,自閉症,生理学,脳・神経,行動学,時計遺伝子,脳神経疾患,クローニング,概日リズム, # of Research Projects：69, # of Research Products：591, Ongoing Project：自閉症における社会性回路遷移機構の解明
10. [XLS] T120 - NRSA Individ Fellows - R1120.xls
... Cherskov, Adriana, 5, F30, NIMH, F30MH123074-03, 1, $52,694, YALE UNIVERSITY, YALE ... Stream, Kendra Leigh, 5, F32, NIDDK, F32DK131695-02, 1, $78,428, UNIVERSITY ...
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11. [PDF] The Pattern Seekers
Bullmore, Bhismadev Chakrabarti, Tony Charman, Emma Chapman, Adriana. Cherskov ... “Segmentation of the speech stream in a non-human primate: Statistical.
12. a13 control mouse: Topics by Science.gov
... Cherskov, Adriana; Miyazaki, Taisuke; Watanabe, Masahiko; Takumi, Toru; Kano ... twitch muscles to overload. Males of eight laboratory mouse strains ...
13. [PDF] 2010 Candidates for the Presidential Scholars Program -- April 2010 (PDF)
IL - Carol Stream - Alejandro A. Argueta, Benet Academy. IL - Carol ... WA - Redmond - Adriana Cherskov, Unknown High School. WA - Redmond - Erika O ...
14. Lhx6 Activity Is Required for the Normal Migration and Specification ...
21 mrt 2007 · ... stream that extended well into the hippocampal anlage (Fig. 7D) ... Adriana Cherskov, Mo Yang, Anahita Amiri, Gianfilippo Coppola ...
The cerebral cortex contains two main neuronal cell populations, the excitatory glutamatergic (pyramidal) neurons and the inhibitory interneurons, which synthesize GABA and constitute 20–30% of all cortical neurons. In contrast to the mostly hom*ogeneous population of projection neurons, cortical interneurons are characterized by remarkable morphological, molecular, and functional diversity. Among the markers that have been used to classify cortical interneurons are the calcium-binding proteins parvalbumin and calretinin and the neuropeptide somatostatin, which in rodents identify mostly nonoverlapping interneuron subpopulations. Pyramidal neurons are born during embryogenesis in the ventricular zone of the dorsal telencephalon, whereas cortical interneurons are generated in the subpallium and reach the cortex by tangential migration. On completion of tangential migration, cortical interneurons switch to a radial mode of migration and enter the cortical plate. Although the mechanisms that control the generation of interneuron diversity are currently unknown, it has been proposed that their site of origin in the ventral forebrain determines their specification into defined neurochemical subgroups. Here, we show that Lhx6 , a gene induced in the medial ganglionic eminence and maintained in parvalbumin- and somatostatin-positive interneurons, is required for the specification of these neuronal subtypes in the neocortex and the hippocampus. We also show that Lhx6 activity is requi...
